Mechanisims of asthma and allergic disease – 1079. Evidence of platelet activation in asthmatic patients
نویسندگان
چکیده
Background Animal models of allergic asthma indicate that intravascular platelet activation is essentail for the development of allergen induced chronic airway inflammation. P2Y12, the third CysLT receptor, is expressed on platelets and has been an important pathophysiological role in LTE4 mediated pulmonary inflammation. We investigated platelet activation status in asthmatic patients compared to controls.
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